Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | BCL9 | O00512 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15412162 | 0.81 | KMT2A (0.43) | ALDH1A1LMNAMAPTHTTKMT2A | |
| SCHEMBL15412367 | 0.79 | KMT2A (0.44) | ALDH1A1LMNAMAPTHTTKMT2A | |
| SCHEMBL20089608 | 0.78 | KMT2A (0.43) | ALDH1A1LMNAMAPTHTTKMT2A | |
| SCHEMBL20089606 | 0.75 | KMT2A (0.68) | ALDH1A1LMNAMAPTHTTKMT2A | |
| SCHEMBL10233491 | 0.74 | PRSS1 (0.46) | L3MBTL1ALDH1A1LMNAMAPTHTT | |
| SCHEMBL13158898 | 0.71 | BCL9 (0.68) | ALDH1A1LMNAMAPTHTTKMT2A | |
| Acetic Acid SCHEMBL23429845 | 0.68 | HRH3 (0.56) | HRH3L3MBTL1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL3551022 | 0.68 | KMT2A (0.64) | ALDH1A1LMNAMAPTHTTKMT2A | |
| SCHEMBL6243481 | 0.67 | L3MBTL1 (0.49) | HRH3L3MBTL1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL7768079 | 0.67 | HRH3 (0.84) | HRH3HDAC8HDAC6PYCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3315126-A1 | CONJUGATE OF POLYETHYLENE GLYCOL AND ANESTHETIC, AND PREPARATION METHOD THEREOF | Jenkem Technology Co. Ltd. (Tianjin) (CN) | 2018-05-02 | — | — | EP | disclosed |