Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | BCL9 | O00512 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15412367 | 0.85 | KMT2A (0.44) | KMT2AMAPTALDH1A1LMNAHTT | |
| SCHEMBL15412162 | 0.84 | KMT2A (0.43) | KMT2AMAPTALDH1A1LMNAHTT | |
| SCHEMBL10233491 | 0.80 | PRSS1 (0.46) | KMT2AMAPTALDH1A1LMNAHTT | |
| SCHEMBL20117849 | 0.78 | HRH3 (0.48) | KMT2AMAPTALDH1A1LMNAHTT | |
| SCHEMBL20089606 | 0.77 | KMT2A (0.68) | KMT2AMAPTALDH1A1LMNAHTT | |
| SCHEMBL13158898 | 0.76 | BCL9 (0.68) | KMT2AMAPTALDH1A1LMNAHTT | |
| SCHEMBL20095263 | 0.74 | KMT2A (0.43) | KMT2AMAPTALDH1A1LMNAHTT | |
| SCHEMBL23635274 | 0.73 | KMT2A (0.57) | KMT2AMAPTALDH1A1LMNAHTT | |
| SCHEMBL21470145 | 0.73 | KMT2A (0.57) | KMT2AMAPTALDH1A1LMNAHTT | |
| SCHEMBL7878468 | 0.73 | KMT2A (0.45) | KMT2AMAPTALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11654198-B2 | Application of combination of polyethylene glycol and local anesthetic in non-narcotic analgesia | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2023-05-23 | — | — | US | disclosed |
| US-11654198-B2 | Application of combination of polyethylene glycol and local anesthetic in non-narcotic analgesia | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2023-05-23 | — | — | US | disclosed |
| EP-3315126-B1 | CONJUGATE OF POLYETHYLENE GLYCOL AND ANESTHETIC, AND PREPARATION METHOD THEREOF | JENKEM TECH CO LTD TIANJIN (CN) | 2022-01-19 | — | — | EP | disclosed |
| US-20200147228-A1 | APPLICATION OF COMBINATION OF POLYETHYLENE GLYCOL AND LOCAL ANESTHETIC IN NON-NARCOTIC ANALGESIA | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2020-05-14 | — | — | US | disclosed |
| EP-3315126-A1 | CONJUGATE OF POLYETHYLENE GLYCOL AND ANESTHETIC, AND PREPARATION METHOD THEREOF | Jenkem Technology Co. Ltd. (Tianjin) (CN) | 2018-05-02 | — | — | EP | disclosed |
| US-20180110867-A1 | CONJUGATE OF POLYETHYLENE GLYCOL AND ANESTHETIC, AND PREPARATION METHOD THEREOF | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2018-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200147228-A1 | APPLICATION OF COMBINATION OF POLYETHYLENE GLYCOL AND LOCAL ANESTHETIC IN NON-NARCOTIC ANALGESIA | OPRL1, OPRK1, OPRM1 | KMT2A 1703/4885MAPT 1887/4885ALDH1A1 689/4885 |
| US-20180110867-A1 | CONJUGATE OF POLYETHYLENE GLYCOL AND ANESTHETIC, AND PREPARATION METHOD THEREOF | OPRL1, OGFR, F12 | KMT2A 1586/4885MAPT 3236/4885ALDH1A1 945/4885 |
| US-11654198-B2 | Application of combination of polyethylene glycol and local anesthetic in non-narcotic analgesia | OPRL1, OPRK1, OPRM1 | KMT2A 1703/4885MAPT 1887/4885ALDH1A1 689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.