Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 18/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20118124 | 0.83 | P2RX7 (0.44) | P2RX7 | |
| SCHEMBL20118173 | 0.83 | P2RX7 (0.46) | P2RX7 | |
| SCHEMBL20118192 | 0.82 | P2RX7 (0.45) | P2RX7 | |
| SCHEMBL18216046 | 0.82 | KMT2A (0.42) | P2RX7DRD2 | |
| SCHEMBL18208388 | 0.82 | KMT2A (0.42) | P2RX7DRD2 | |
| SCHEMBL20118224 | 0.81 | P2RX7 (0.48) | P2RX7 | |
| SCHEMBL18208871 | 0.72 | KMT2A (0.44) | P2RX7 | |
| SCHEMBL18209085 | 0.70 | KMT2A (0.42) | P2RX7 | |
| SCHEMBL20205075 | 0.69 | P2RX7 (0.37) | P2RX7DRD2DRD4 | |
| SCHEMBL20118162 | 0.68 | KMT2A (0.40) | P2RX7DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018078009-A1 | AMIDO-SUBSTITUTED CYCLOHEXANE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-03 | — | — | WO | disclosed |