Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 14/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | ARRB1 | P49407 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20118173 | 0.89 | P2RX7 (0.46) | P2RX7 | |
| SCHEMBL20118192 | 0.89 | P2RX7 (0.45) | P2RX7ALDH1A1 | |
| SCHEMBL20118180 | 0.83 | P2RX7 (0.41) | P2RX7 | |
| SCHEMBL20118165 | 0.78 | ALDH1A1 (0.50) | P2RX7DPP4ALDH1A1 | |
| SCHEMBL18209064 | 0.78 | PSEN1 (0.39) | P2RX7OPRM1 | |
| SCHEMBL18216089 | 0.78 | PSEN1 (0.39) | P2RX7OPRM1 | |
| SCHEMBL6944544 | 0.70 | ACHE (0.48) | DPP4ALDH1A1 | |
| SCHEMBL20118219 | 0.70 | P2RX7 (0.53) | P2RX7ALDH1A1 | |
| SCHEMBL18208519 | 0.67 | P2RX7 (0.44) | P2RX7 | |
| SCHEMBL18208520 | 0.67 | P2RX7 (0.44) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018078009-A1 | AMIDO-SUBSTITUTED CYCLOHEXANE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-03 | — | — | WO | disclosed |