Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2069877 | 0.95 | BDKRB2 (0.36) | MAPK1LMNATP53CYP1A2CYP3A4 | |
| SCHEMBL3548162 | 0.90 | TP53 (0.32) | LMNATP53 | |
| SCHEMBL1145324 | 0.72 | CSNK1E (0.41) | LMNAALDH1A1SMN1; SMN2CSNK1EPPARG | |
| SCHEMBL3589049 | 0.71 | CSNK1E (0.43) | ALDH1A1CSNK1EPPARGPPARAPRSS1 | |
| SCHEMBL3590952 | 0.71 | CSNK1E (0.43) | ALDH1A1CSNK1EPPARGPPARAPRSS1 | |
| SCHEMBL3594986 | 0.71 | CSNK1E (0.43) | ALDH1A1CSNK1EPPARGPPARAPRSS1 | |
| SCHEMBL3582718 | 0.71 | CSNK1E (0.43) | ALDH1A1CSNK1EPPARGPPARAPRSS1 | |
| SCHEMBL3584428 | 0.71 | CSNK1E (0.43) | ALDH1A1CSNK1EPPARGPPARAPRSS1 | |
| SCHEMBL3587334 | 0.71 | CSNK1E (0.43) | ALDH1A1CSNK1EPPARGPPARAPRSS1 | |
| SCHEMBL3594352 | 0.71 | CSNK1E (0.43) | ALDH1A1CSNK1EPPARGPPARAPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964599-B2 | Therapeutic compounds | ALLERGAN, INC. (US) | 2011-06-21 | — | — | US | disclosed |
| US-20090281104-A1 | Therapeutic Compounds | ALLERGAN, INC. (US) | 2009-11-12 | — | — | US | disclosed |
| EP-2029518-A2 | CYCLOPENTANE-DERIVATIVES AND THEIR USE AS OCULAR HYPOTENSIVE AGENTS | Allergan, Inc. (US) | 2009-03-04 | — | — | EP | disclosed |
| US-7476755-B2 | Therapeutic compounds | ALLERGAN, INC. (US) | 2009-01-13 | — | — | US | disclosed |
| WO-2007130890-A2 | CYCLOPENTANE-DERIVATIVES AND THEIR USE AS OCULAR HYPOTENSIVE AGENTS | ALLERGAN, INC. (US) | 2007-11-15 | — | — | WO | disclosed |
| US-20070259929-A1 | Therapeutic Compounds | ALLERGAN, INC. | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259929-A1 | Therapeutic Compounds | PIGO, CYC1, COXFA4L2 | MAPK1 4318/4885LMNA 1423/4885TP53 1668/4885 |
| US-20090281104-A1 | Therapeutic Compounds | SLC10A1, ABCB11, GUSB | MAPK1 3793/4885LMNA 2172/4885TP53 776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.