Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL903609 | 0.87 | PPARG (0.46) | LMNAKCNH2ALDH1A1KDM4E | |
| SCHEMBL20118857 | 0.76 | MEN1 (0.43) | LMNAMEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL3083944 | 0.74 | KCNH2 (0.52) | LMNAMAPTKMT2AKCNJ1KCNH2 | |
| SCHEMBL27435752 | 0.74 | ALDH1A1 (0.54) | LMNAMAPTTHRBNPSR1FBP1 | |
| SCHEMBL31001663 | 0.72 | CYP4F2 (0.51) | THRBMEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL1687901 | 0.71 | TSHR (0.40) | LMNAHTTMAPTMEN1KMT2A | |
| SCHEMBL15199327 | 0.69 | ALDH1A1 (0.56) | LMNAHTTMAPTTHRBMEN1 | |
| SCHEMBL11279345 | 0.69 | PTPRC (0.45) | LMNATHRBCYP1A2TAAR1ALDH1A1 | |
| SCHEMBL11272896 | 0.69 | SMN1; SMN2 (0.40) | LMNANPSR1MEN1KMT2ACYP4F2 | |
| SCHEMBL14510426 | 0.69 | ALDH1A1 (0.42) | MAPTTHRBNPSR1FBP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621886-B1 | PROCESS FOR MAKING FINGOLIMOD | SYNTHON BV (NL) | 2018-05-02 | — | — | EP | disclosed |