Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.45 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.45 |
| ▸ | GPR183 | P32249 | 1/20 | 0.45 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20119271 | 0.87 | LMNA (0.40) | KCNH2ALDH1A1KDM4ELMNA | |
| SCHEMBL903619 | 0.79 | S1PR1 (0.56) | PPARGPPARASPHK2SPHK1TNNC1 | |
| SCHEMBL18118825 | 0.77 | PPARA (0.52) | PPARGPPARASPHK2SPHK1TNNC1 | |
| SCHEMBL2723128 | 0.75 | TNNC1 (0.50) | SPHK2TNNC1S1PR1S1PR4S1PR3 | |
| SCHEMBL903628 | 0.74 | ATM (0.68) | PPARGPPARASPHK2TNNC1S1PR1 | |
| SCHEMBL8538203 | 0.74 | ATM (0.68) | PPARGPPARASPHK2TNNC1S1PR1 | |
| SCHEMBL903515 | 0.74 | S1PR1 (0.61) | SPHK2SPHK1TNNC1S1PR1S1PR4 | |
| SCHEMBL1286794 | 0.73 | KCNH2 (0.46) | SPHK2SPHK1TNNC1S1PR1S1PR4 | |
| SCHEMBL12912511 | 0.72 | MEN1 (0.51) | PPARGPPARASPHK2TNNC1S1PR1 | |
| SCHEMBL7615830 | 0.71 | S1PR1 (0.57) | S1PR1S1PR4S1PR3S1PR5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041359-A1 | PROCESS FOR MAKING FINGOLIMOD | SYNTHON B.V. (NL) | 2012-04-05 | — | — | WO | disclosed |
| WO-2012041707-A1 | PROCESS FOR MAKING FINGOLIMOD | SYNTHON BV (NL) | 2012-04-05 | — | — | WO | disclosed |
| WO-2012041405-A1 | PROCESS FOR MAKING FINGOLIMOD | SYNTHON B.V. (NL) | 2012-04-05 | — | — | WO | disclosed |