Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2012931 | 0.99 | HTR1A (0.42) | HTR1ADRD2MAOBKDM4ELMNA | |
| SCHEMBL2011766 | 0.87 | HTR1A (0.40) | HTR1ADRD2KDM4ELMNACHRM2 | |
| SCHEMBL10629321 | 0.83 | MAOB (0.45) | MAOBLMNAALDH1A1HPGD | |
| SCHEMBL12894176 | 0.79 | MAOB (0.44) | MAOBLMNAALDH1A1HPGD | |
| SCHEMBL13623334 | 0.78 | HTR1A (0.43) | HTR1ADRD2KDM4ELMNACHRM2 | |
| SCHEMBL3841214 | 0.78 | TDP1 (0.51) | HTR1ADRD2KDM4ELMNACHRM2 | |
| SCHEMBL7292776 | 0.78 | HTR1A (0.46) | HTR1ADRD2KDM4ELMNACHRM2 | |
| SCHEMBL2011929 | 0.78 | HTR1A (0.44) | HTR1ADRD2KDM4ELMNACHRM2 | |
| Hydrochloric Acid SCHEMBL2012002 | 0.77 | TDP1 (0.50) | HTR1ADRD2KDM4ELMNACHRM2 | |
| SCHEMBL10867623 | 0.77 | HTR1A (0.45) | HTR1ADRD2KDM4ELMNACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513055-A1 | PROCESS FOR THE PREPARATION OF ROPINIROLE AND SALTS THEREOF | Pharmathen S.A. (GR) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011072704-A1 | PROCESS FOR THE PREPARATION OF ROPINIROLE AND SALTS THEREOF | PHARMATHEN S.A. (GR) | 2011-06-23 | — | — | WO | disclosed |