SCHEMBL20119935

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20119664	0.89	KCNH3 (0.38)	CDK2CCNE1JAK2IGF1RPIM1
	SCHEMBL20119888	0.85	ESR1 (0.42)	CDK2CCNE1PDE2AYTHDC1CDK1
	SCHEMBL20119750	0.82	PDE2A (0.40)	CDK2CCNE1JAK2IGF1RPIM1
	SCHEMBL20119716	0.78	HRH4 (0.39)	CDK2CCNE1PDE2AYTHDC1CDK1
	SCHEMBL20119396	0.76	KMT2A (0.49)	CHRM4ADORA3ADORA2AADORA2B
	SCHEMBL20119808	0.75	CDK2 (0.41)	CDK2CCNE1JAK2IGF1RPIM1
	SCHEMBL20119730	0.73	PIM1 (0.38)	CDK2CCNE1JAK2IGF1RPIM1
	SCHEMBL20119746	0.73	PDE2A (0.40)	CDK2CCNE1PDE2AYTHDC1CDK1
	SCHEMBL20119914	0.72	PDE2A (0.43)	CDK2CCNE1JAK2IGF1RPIM1
	SCHEMBL20119422	0.70	KCNH3 (0.41)	CDK2CCNE1JAK2IGF1RPIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.