Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20119926 | 0.82 | KCNH3 (0.37) | KCNH3ADORA3 | |
| SCHEMBL20119707 | 0.81 | KCNH3 (0.32) | KCNH3ADORA3 | |
| SCHEMBL20119762 | 0.78 | PDE10A (0.36) | KCNH3ADORA3 | |
| SCHEMBL20119754 | 0.76 | KCNH3 (0.34) | KCNH3ADORA3 | |
| SCHEMBL25873886 | 0.76 | KCNH3 (0.37) | KCNH3ADORA3 | |
| SCHEMBL20119803 | 0.75 | CDK2 (0.36) | KCNH3 | |
| SCHEMBL20119932 | 0.75 | KCNH3 (0.36) | KCNH3 | |
| SCHEMBL20119923 | 0.74 | KDM4C (0.33) | KCNH3ADORA3 | |
| SCHEMBL20119820 | 0.74 | KCNH3 (0.36) | KCNH3ADORA3 | |
| SCHEMBL20119531 | 0.73 | KDM4C (0.37) | KCNH3ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118748-A1 | Compounds for Improving mRNA Splicing | THE GENERAL HOSPITAL CORPORATION | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118748-A1 | Compounds for Improving mRNA Splicing | RTCB, RBM17, HNRNPA2B1 | KCNH3 3654/4885ADORA3 2060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.