Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | LGMN | Q99538 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PIK3C2B | O00750 | 5/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TPH1 | P17752 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18509763 | 0.85 | MAPT (0.41) | LMNANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL18000151 | 0.85 | MAPT (0.41) | LMNANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL18029390 | 0.82 | PTGS2 (0.41) | PTGS2LGMNLMNANPC1SMN1; SMN2 | |
| SCHEMBL26333089 | 0.81 | IKBKB (0.31) | LGMNIKBKBBRD4KDM4E | |
| SCHEMBL20120034 | 0.80 | GRIK1 (0.38) | LGMNLMNANPC1SMN1; SMN2MAPT | |
| SCHEMBL18029350 | 0.80 | PLA2G4A (0.45) | PTGS2LMNAAOC3NPC1SMN1; SMN2 | |
| SCHEMBL18029387 | 0.78 | PTGS2 (0.43) | PTGS2NPC1SMN1; SMN2MAPTTPH1 | |
| SCHEMBL18029351 | 0.73 | MAPT (0.38) | PTGS2LMNANPC1SMN1; SMN2MAPT | |
| SCHEMBL18000395 | 0.73 | MAPT (0.38) | PTGS2LMNANPC1SMN1; SMN2MAPT | |
| SCHEMBL19871274 | 0.73 | MAPT (0.40) | MAPTMEN1ALDH1A1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081456-A1 | HIGHLY ACTIVE SELF-SUFFICIENT NITRATION BIOCATALYSTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-05-03 | — | — | WO | disclosed |