Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12786457 | 1.00 | SMN1; SMN2 (0.40) | SMN1; SMN2NAPRTHTTALDH1A1L3MBTL1 | |
| SCHEMBL18789917 | 0.83 | ALDH5A1 (0.37) | SMN1; SMN2ALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL17916791 | 0.82 | SMN1; SMN2 (0.35) | SMN1; SMN2NAPRTHTTALDH1A1L3MBTL1 | |
| SCHEMBL12831243 | 0.80 | SMN1; SMN2 (0.39) | SMN1; SMN2NAPRTHTTALDH1A1L3MBTL1 | |
| SCHEMBL28795376 | 0.80 | SMN1; SMN2 (0.39) | SMN1; SMN2NAPRTHTTALDH1A1L3MBTL1 | |
| SCHEMBL14568166 | 0.80 | SMN1; SMN2 (0.39) | SMN1; SMN2NAPRTHTTALDH1A1L3MBTL1 | |
| SCHEMBL18509288 | 0.79 | SMN1; SMN2 (0.40) | SMN1; SMN2NAPRTHTTALDH1A1L3MBTL1 | |
| SCHEMBL1073773 | 0.76 | AKT1 (0.50) | SMN1; SMN2NAPRTALDH1A1MEN1KMT2A | |
| SCHEMBL1073772 | 0.76 | AKT1 (0.50) | SMN1; SMN2NAPRTALDH1A1MEN1KMT2A | |
| SCHEMBL14780997 | 0.76 | AKT1 (0.50) | SMN1; SMN2NAPRTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220389306-A1 | ZWITTERIONIC COMPOUNDS FOR NON-LINEAR OPTICS, SENSORS, AND SPECTROSCOPY | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. | 2022-12-08 | — | — | US | disclosed |
| EP-3932911-A1 | POLARIZATION SOURCE FOR DYNAMIC NUCLEAR POLARIZATION, COMPOSITION, COMPOSITION FOR DYNAMIC NUCLEAR POLARIZATION, METHOD FOR HYPERPOLARIZATION, HYPERPOLARIZED SUBSTANCE AND NMR MEASUREMENT METHOD | Kyushu University, National University Corporation (JP) | 2022-01-05 | — | — | EP | disclosed |
| US-10833281-B2 | Organic electroluminescence composition, material for organic electroluminescence element, solution of material for organic electroluminescence element, and organic electroluminescence element | IDEMITSU KOSAN CO., LTD. (JP) | 2020-11-10 | — | — | US | disclosed |
| EP-2477999-B1 | FORMULATIONS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-01-23 | — | — | EP | disclosed |
| WO-2018081456-A1 | HIGHLY ACTIVE SELF-SUFFICIENT NITRATION BIOCATALYSTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10833281-B2 | Organic electroluminescence composition, material for organic electroluminescence element, solution of material for organic electroluminescence element, and organic electroluminescence element | SLCO4C1, SLCO2A1, SLCO1A2 | SMN1; SMN2 1581/4885NAPRT 1626/4885HTT 333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.