SCHEMBL20120205

SCHEMBL20120205

Cc1ccccccc([N+](=O)[O-])cc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.78
HSD17B10 Q99714 1/20 0.78
ALDH1A1 P00352 3/20 0.70
LMNA P02545 3/20 0.70
TSHR P16473 3/20 0.61
L3MBTL1 Q9Y468 2/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
ALOX12 P18054 2/20 0.53
CRHBP P24387 2/20 0.53
CRHR2 Q13324 2/20 0.53
ATM Q13315 1/20 0.53
TLR9 Q9NR96 1/20 0.53
HPGD P15428 1/20 0.53
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
NFE2L2 Q16236 1/20 0.51
MAOA P21397 1/20 0.47
MAOB P27338 1/20 0.47
BCHE P06276 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Nitrotoluene SCHEMBL11648100 0.98 ACHE (0.82) ACHEHSD17B10ALDH1A1LMNATSHR
Nitrobenzene SCHEMBL4937722 0.96 LMNA (0.76) ACHEHSD17B10ALDH1A1LMNATSHR
4-Nitrotoluene SCHEMBL8492937 0.93 ACHE (0.90) ACHEHSD17B10ALDH1A1LMNATSHR
4-Nitrotoluene SCHEMBL73252 0.89 ACHE (1.00) ACHEHSD17B10ALDH1A1LMNATSHR
4-Nitrotoluene SCHEMBL2484690 0.89 ACHE (1.00) ACHEHSD17B10ALDH1A1LMNATSHR
4-Nitrotoluene SCHEMBL11183878 0.87 HSD17B10 (0.78) ACHEHSD17B10ALDH1A1LMNATSHR
4-Nitrotoluene SCHEMBL6751959 0.86 ACHE (0.95) ACHEHSD17B10ALDH1A1LMNATSHR
4-Nitrotoluene SCHEMBL9402408 0.86 ACHE (0.95) ACHEHSD17B10ALDH1A1LMNATSHR
4-Nitrotoluene SCHEMBL9734611 0.86 ACHE (0.95) ACHEHSD17B10ALDH1A1LMNATSHR
4-Nitrotoluene SCHEMBL28481150 0.86 ACHE (0.95) ACHEHSD17B10ALDH1A1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3315486-A1 METHOD FOR PRODUCING AROMATIC COMPOUND Tosoh Corporation (JP) 2018-05-02 EP disclosed