Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.32 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | ICMT | O60725 | 4/20 | 0.31 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2013843 | 0.84 | BCL2 (0.48) | BCL2PIK3CDGRIN2BNT5EICMT | |
| Trifluoroacetic Acid SCHEMBL2013841 | 0.81 | BCL2 (0.42) | BCL2PIK3CDGRIN2BNT5EICMT | |
| Trifluoroacetic Acid SCHEMBL2012078 | 0.80 | BCL2 (0.41) | BCL2PIK3CDGRIN2BNT5EICMT | |
| SCHEMBL12403232 | 0.77 | BCL2 (0.48) | BCL2PIK3CDGRIN2BNT5EDPP4 | |
| SCHEMBL2165713 | 0.76 | BCL2 (0.42) | BCL2PIK3CDGRIN2BNT5EICMT | |
| Trifluoroacetic Acid SCHEMBL2012076 | 0.76 | BCL2 (0.53) | BCL2PIK3CDGRIN2BNT5EADAMTS5 | |
| SCHEMBL12491178 | 0.75 | BCL2 (0.47) | BCL2PIK3CDNT5EDPP4 | |
| SCHEMBL2019261 | 0.75 | PIK3CD (0.44) | BCL2PIK3CDGRIN2BNT5E | |
| SCHEMBL2038100 | 0.72 | PIK3CD (0.41) | BCL2PIK3CD | |
| Trifluoroacetic Acid SCHEMBL2038097 | 0.72 | PIK3CD (0.49) | BCL2PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075630-A1 | SUBSTITUTED FUSED ARYL AND HETEROARYL DERIVATIVES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2011-06-23 | — | — | WO | disclosed |