SCHEMBL20121048

SCHEMBL20121048

CC/C(C)=C/[C@@H](C)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.35
ALDH1A1 P00352 2/20 0.35
FFAR3 O14843 1/20 0.35
GRIN2D O15399 1/20 0.34
GRIN3B O60391 1/20 0.34
GRIN1 Q05586 1/20 0.34
GRIN2A Q12879 1/20 0.34
GRIN2B Q13224 1/20 0.34
GRIN2C Q14957 1/20 0.34
GRIN3A Q8TCU5 1/20 0.34
TP53 P04637 1/20 0.33
CA2 P00918 1/20 0.32
MAPK1 P28482 1/20 0.32
CHRM1 P11229 1/20 0.32
AKR1A1 P14550 1/20 0.32
CHRM3 P20309 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
ADRA1A P35348 1/20 0.32
HRH1 P35367 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1782242 0.83 TDP1 (0.36) TDP1ALDH1A1FFAR3
SCHEMBL1782240 0.83 TDP1 (0.36) TDP1ALDH1A1FFAR3
SCHEMBL16076460 0.79 TSHR (0.33) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL14763929 0.79 TSHR (0.33) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL27175925 0.79 TSHR (0.33) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL24427092 0.79 ALDH1A1 (0.38) ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL14763928 0.79 TSHR (0.33) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL22500762 0.79 CES1 (0.45) TDP1ALDH1A1TP53CA2MAPK1
SCHEMBL22500761 0.79 CES1 (0.45) TDP1ALDH1A1TP53CA2MAPK1
SCHEMBL7427084 0.78 FFAR3 (0.36) TDP1FFAR3TP53CA2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9963481-B2 Chiral oligomeric pentenoate amides as bio-oligomer mimetics THE SCRIPPS RESEARCH INSTITUTE (US) 2018-05-08 US disclosed