SCHEMBL24427092

SCHEMBL24427092

C/C(=C\C(C)C(=O)O)CC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
LDHA P00338 1/20 0.35
SRR Q9GZT4 1/20 0.35
FOLH1 Q04609 4/20 0.33
NAALAD2 Q9Y3Q0 2/20 0.33
CYP1A2 P05177 1/20 0.33
RECQL P46063 1/20 0.33
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2A Q12879 1/20 0.33
GRIN2B Q13224 1/20 0.33
GRIN2C Q14957 1/20 0.33
GRIN3A Q8TCU5 1/20 0.33
TP53 P04637 1/20 0.32
KISS1R Q969F8 2/20 0.32
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13978576 0.81 LDHA (0.38) ALDH1A1LDHASRRFOLH1NAALAD2
SCHEMBL28483566 0.80 LMNA (0.42) CYP1A2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL20121048 0.79 TDP1 (0.35) ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL27175925 0.77 TSHR (0.33) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL14763929 0.77 TSHR (0.33) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL14763928 0.77 TSHR (0.33) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL16076460 0.77 TSHR (0.33) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL22500738 0.72 HDAC1 (0.37) ALDH1A1LDHASRRCYP1A2GRIN2D
SCHEMBL22500762 0.72 CES1 (0.45) ALDH1A1TP53MEN1KMT2A
SCHEMBL22500761 0.72 CES1 (0.45) ALDH1A1TP53MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3494093-B1 METHODS AND USES OF DISSOLVED ORGANIC MATERIAL FRACTIONS FOR BINDING METAL IONS NOBLEGEN INC (CA) 2022-05-18 EP disclosed