Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.63 |
| ▸ | TSPO | P30536 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | BAX | Q07812 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18721786 | 0.91 | DNM1 (0.76) | DNM1TSPOMAPTHTTNPSR1 | |
| SCHEMBL407045 | 0.89 | DNM1 (0.80) | DNM1TSPOMAPTHTTNPSR1 | |
| SCHEMBL17932994 | 0.86 | TSPO (0.65) | DNM1TSPOMAPTHTTNPSR1 | |
| SCHEMBL30940007 | 0.86 | TSPO (0.65) | DNM1TSPOMAPTHTTNPSR1 | |
| SCHEMBL14700982 | 0.83 | DNM1 (0.57) | DNM1TSPOMAPTHTTNPSR1 | |
| SCHEMBL16923522 | 0.79 | DNM1 (0.77) | DNM1TSPOMAPTHTTNPSR1 | |
| SCHEMBL18721925 | 0.79 | DNM1 (0.77) | DNM1TSPOMAPTHTTNPSR1 | |
| SCHEMBL18721999 | 0.78 | TSPO (0.68) | DNM1TSPOMAPTHTTNPSR1 | |
| SCHEMBL410147 | 0.78 | DNM1 (1.00) | DNM1TSPOMAPTHTTNPSR1 | |
| SCHEMBL29351340 | 0.78 | DNM1 (1.00) | DNM1TSPOMAPTHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9962368-B2 | Pro-neurogenic compounds | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2018-05-08 | — | — | US | disclosed |