Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.84 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.84 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.84 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.84 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.84 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.84 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.84 |
| ▸ | TP53 | P04637 | 1/20 | 0.84 |
| ▸ | POLB | P06746 | 1/20 | 0.84 |
| ▸ | MAPT | P10636 | 1/20 | 0.84 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.61 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.61 |
| ▸ | F13A1 | P00488 | 1/20 | 0.58 |
| ▸ | TGM2 | P21980 | 1/20 | 0.58 |
| ▸ | ACVRL1 | P37023 | 4/20 | 0.57 |
| ▸ | FLT4 | P35916 | 3/20 | 0.53 |
| ▸ | KDR | P35968 | 3/20 | 0.53 |
| ▸ | FLT3 | P36888 | 3/20 | 0.53 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30163150 | 0.95 | LMNA (0.88) | LMNASMN1; SMN2ESR2ALDH1A1HSP90AA1 | |
| SCHEMBL31217635 | 0.95 | LMNA (0.88) | LMNASMN1; SMN2ESR2ALDH1A1HSP90AA1 | |
| SCHEMBL29737259 | 0.95 | LMNA (0.88) | LMNASMN1; SMN2ESR2ALDH1A1HSP90AA1 | |
| SCHEMBL869065 | 0.95 | LMNA (0.88) | LMNASMN1; SMN2ESR2ALDH1A1HSP90AA1 | |
| Zeranol SCHEMBL2602612 | 0.91 | LMNA (1.00) | LMNASMN1; SMN2ESR2ALDH1A1HSP90AA1 | |
| Zeranol SCHEMBL31122084 | 0.91 | LMNA (1.00) | LMNASMN1; SMN2ESR2ALDH1A1HSP90AA1 | |
| Zeranol SCHEMBL109174 | 0.91 | LMNA (1.00) | LMNASMN1; SMN2ESR2ALDH1A1HSP90AA1 | |
| Zeranol SCHEMBL10773090 | 0.91 | LMNA (1.00) | LMNASMN1; SMN2ESR2ALDH1A1HSP90AA1 | |
| Zeranol SCHEMBL9592548 | 0.91 | LMNA (1.00) | LMNASMN1; SMN2ESR2ALDH1A1HSP90AA1 | |
| Taleranol SCHEMBL29554859 | 0.91 | LMNA (1.00) | LMNASMN1; SMN2ESR2ALDH1A1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9962326-B2 | Compositions comprising paulownia tomentosa wood extracts and uses thereof | JOHNSON & JOHNSON CONSUMER INC. (US) | 2018-05-08 | — | — | US | disclosed |