Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.88 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.88 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.88 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.88 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.88 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.88 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.88 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.88 |
| ▸ | TP53 | P04637 | 1/20 | 0.88 |
| ▸ | POLB | P06746 | 1/20 | 0.88 |
| ▸ | MAPT | P10636 | 1/20 | 0.88 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.66 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.66 |
| ▸ | F13A1 | P00488 | 1/20 | 0.62 |
| ▸ | TGM2 | P21980 | 1/20 | 0.62 |
| ▸ | ACVRL1 | P37023 | 4/20 | 0.59 |
| ▸ | FLT4 | P35916 | 4/20 | 0.57 |
| ▸ | KDR | P35968 | 4/20 | 0.57 |
| ▸ | FLT3 | P36888 | 4/20 | 0.57 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29737259 | 1.00 | LMNA (0.88) | LMNASMN1; SMN2ESR2ALDH1A1HSP90AA1 | |
| SCHEMBL31217635 | 1.00 | LMNA (0.88) | LMNASMN1; SMN2ESR2ALDH1A1HSP90AA1 | |
| SCHEMBL30163150 | 1.00 | LMNA (0.88) | LMNASMN1; SMN2ESR2ALDH1A1HSP90AA1 | |
| SCHEMBL20121859 | 0.95 | LMNA (0.84) | LMNASMN1; SMN2ESR2ALDH1A1HSP90AA1 | |
| Zeranol SCHEMBL2602612 | 0.94 | LMNA (1.00) | LMNASMN1; SMN2ESR2ALDH1A1HSP90AA1 | |
| Zeranol SCHEMBL9592548 | 0.94 | LMNA (1.00) | LMNASMN1; SMN2ESR2ALDH1A1HSP90AA1 | |
| Zeranol SCHEMBL109174 | 0.94 | LMNA (1.00) | LMNASMN1; SMN2ESR2ALDH1A1HSP90AA1 | |
| Zeranol SCHEMBL31122084 | 0.94 | LMNA (1.00) | LMNASMN1; SMN2ESR2ALDH1A1HSP90AA1 | |
| Zeranol SCHEMBL10773090 | 0.94 | LMNA (1.00) | LMNASMN1; SMN2ESR2ALDH1A1HSP90AA1 | |
| Zeranol SCHEMBL29554783 | 0.94 | LMNA (1.00) | LMNASMN1; SMN2ESR2ALDH1A1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251813-B1 | IMMUNOSTIMULATING AGENTS | IMCERA Group Inc. (US) | 1993-06-23 | — | — | EP | claimed |
| EP-0299794-B1 | RESORCYLIC ACID LACTONE COMPOUNDS FOR CONTROLLING HELMINTIC PARASITES | IMCERA Group Inc. (US) | 1993-02-03 | — | — | EP | claimed |
| US-4842862-A | ZEARALANE AND DERIVATIVES | INTERNATIONAL MINERALS & CHEMICAL CORP. (US) | 1989-06-27 | — | — | US | claimed |
| EP-0299794-A2 | Resorcylic acid lactone compounds for controlling helmintic parasites | IMCERA Group Inc. (US) | 1989-01-18 | — | — | EP | claimed |
| US-4778821-A | ADMINISTERING RESORCYLIC ACID LACTONE | INTERNATIONAL MINERALS & CHEMICAL CORP. (US) | 1988-10-18 | — | — | US | claimed |
| EP-0251813-A2 | Immunostimulating agents | IMCERA Group Inc. (US) | 1988-01-07 | — | — | EP | claimed |
| US-4088658-A | REACTING HYDROXY COMPOUND WITH A SULFONYL CHLORIDE TO FORM SULFONATE, HYDROGENOLYSIS | IMC CHEMICAL GROUP, INC. (US) | 1978-05-09 | — | — | US | claimed |
| US-12455283-B2 | Methods for screening polypeptides capable of binding specific target molecules and tools related thereto | TEKNOLOGIAN TUTKIMUSKESKUS VTT OY (FI) | 2025-10-28 | — | — | US | disclosed |
| US-10239856-B2 | Synthesis of resorcylic acid lactones useful as therapeutic agents | UNIVERSITY DE STRASBOURG (FR) | 2019-03-26 | — | — | US | disclosed |
| EP-2136799-B1 | MACROCYCLIC COMPOUNDS USEFUL AS INHIBITORS OF KINASES AND HSP90 | UNIV STRASBOURG (FR) | 2017-10-04 | — | — | EP | disclosed |
| EP-2254880-B1 | Macrocyclic prodrug compounds useful as therapeutics | NEXGENIX PHARMACEUTICALS (US) | 2016-08-17 | — | — | EP | disclosed |
| EP-2242359-B1 | SYNTHESIS OF RESORCYLIC ACID LACTONES USEFUL AS THERAPEUTIC AGENTS | UNIV STRASBOURG (FR) | 2016-06-01 | — | — | EP | disclosed |
| CN-101990399-B | Synthetic as the RALs of therapeutic agent | UNIVERSITE DE STRASBOURG (FR) | 2016-05-04 | — | — | CN | disclosed |
| EP-0251813-A2 | Immunostimulating agents | IMCERA Group Inc. (US) | 1988-01-07 | — | — | EP | disclosed |
| EP-0251813-A2 | Immunostimulating agents | IMCERA Group Inc. (US) | 1988-01-07 | — | — | EP | disclosed |
| US-4690948-A | FEEDS RUMEN FERMENTATION EFFICIENCY | INTERNATIONAL MINERALS & CHEMICAL CORP. (US) | 1987-09-01 | — | — | US | disclosed |
| US-4088658-A | REACTING HYDROXY COMPOUND WITH A SULFONYL CHLORIDE TO FORM SULFONATE, HYDROGENOLYSIS | IMC CHEMICAL GROUP, INC. (US) | 1978-05-09 | — | — | US | disclosed |
| US-4062970-A | ANIMAL GROWTH PROMOTERS | IMC CHEMICAL GROUP, INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-4051128-A | ETHERIFICATION | IMC CHEMICAL GROUP, INC. (US) | 1977-09-27 | — | — | US | disclosed |
| US-3960835-A | RUMINANT GROWTH PROMOTER | COMMERCIAL SOLVENTS CORPORATION (US) | 1976-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10239856-B2 | Synthesis of resorcylic acid lactones useful as therapeutic agents | HSP90AA1, HSP90AB1, HSP90AB2P | LMNA 2644/4885SMN1; SMN2 4166/4885ESR2 1670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.