Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC42 | P60953 | 3/20 | 0.51 |
| ▸ | RAC1 | P63000 | 3/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10961188 | 0.85 | PTGS2 (0.74) | CDC42RAC1PTGS2NPC1RAB9A | |
| SCHEMBL10024799 | 0.83 | PTGS2 (0.71) | CDC42RAC1PTGS2NPC1RAB9A | |
| SCHEMBL29449412 | 0.83 | PTGS2 (0.71) | CDC42RAC1PTGS2NPC1RAB9A | |
| SCHEMBL11535191 | 0.83 | CDC42 (0.47) | CDC42RAC1PTGS2NPC1RAB9A | |
| Charcoal, Activated SCHEMBL30824313 | 0.82 | PTGS2 (0.69) | CDC42RAC1PTGS2NPC1RAB9A | |
| Methane SCHEMBL29185931 | 0.82 | PTGS2 (0.69) | CDC42RAC1PTGS2NPC1RAB9A | |
| SCHEMBL11198378 | 0.80 | CDC42 (0.63) | CDC42RAC1PTGS2NPC1RAB9A | |
| SCHEMBL11194406 | 0.79 | CDC42 (0.62) | CDC42RAC1PTGS2NPC1RAB9A | |
| SCHEMBL11603872 | 0.79 | PTGS2 (0.52) | CDC42RAC1PTGS2NPC1RAB9A | |
| SCHEMBL11197122 | 0.77 | PTGS2 (0.47) | CDC42RAC1PTGS2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9962371-B2 | Ready to use ketorolac formulations | RTU PHARMACEUTICALS, LLC (US) | 2018-05-08 | — | — | US | disclosed |