Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.48 |
| ▸ | CPN1 | P15169 | 1/20 | 0.42 |
| ▸ | CPA3 | P15088 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7879260 | 0.84 | CHRM1 (0.46) | CPB2FOLH1CHRM1AKR1A1CHRM3 | |
| SCHEMBL8943729 | 0.78 | FOLH1 (0.46) | CPB2FOLH1CPN1CPA3PTGS1 | |
| SCHEMBL350816 | 0.78 | — | — | |
| SCHEMBL3914888 | 0.77 | CA2 (0.56) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL20621110 | 0.75 | FOLH1 (0.50) | CPB2FOLH1CPA3CHRM1AKR1A1 | |
| SCHEMBL12391770 | 0.75 | CPB2 (0.40) | CPB2CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL8499052 | 0.74 | — | — | |
| SCHEMBL9582293 | 0.74 | — | — | |
| SCHEMBL1408564 | 0.74 | — | — | |
| SCHEMBL29534338 | 0.74 | CPB2 (0.74) | CPB2FOLH1CPN1CPA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963540-B2 | Densely functionalized polymers derived from baylis-hillman adducts | THE UNIVERSITY OF AKRON (US) | 2018-05-08 | — | — | US | disclosed |