Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 2/20 | 0.44 |
| ▸ | TOP2A | P11388 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20122000 | 0.87 | RARB (0.56) | HDAC11HDAC2HDAC1HDAC7HDAC8 | |
| SCHEMBL20122013 | 0.87 | HDAC11 (0.61) | HDAC11HDAC2HDAC1HDAC7HDAC8 | |
| SCHEMBL17916281 | 0.87 | HDAC11 (0.44) | HDAC11HDAC2HDAC1HDAC7HDAC8 | |
| SCHEMBL16516253 | 0.87 | HDAC11 (0.63) | HDAC11HDAC2HDAC1HDAC7HDAC8 | |
| SCHEMBL16516252 | 0.87 | HDAC11 (0.63) | HDAC11HDAC2HDAC1HDAC7HDAC8 | |
| SCHEMBL20122035 | 0.81 | EPHX2 (0.47) | SMN1; SMN2IDH1POLB | |
| SCHEMBL16517400 | 0.75 | RARB (0.74) | HDAC11HDAC2HDAC1HDAC7HDAC8 | |
| SCHEMBL17911574 | 0.75 | RARB (0.74) | HDAC11HDAC2HDAC1HDAC7HDAC8 | |
| SCHEMBL17916353 | 0.74 | RARB (0.50) | HDAC11HDAC2HDAC1HDAC7HDAC8 | |
| SCHEMBL20122027 | 0.74 | HDAC11 (0.52) | HDAC11HDAC2HDAC1HDAC7HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963439-B2 | Specific inhibitors of cytochrome P450 26 retinoic acid hydroxylase | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2018-05-08 | — | — | US | disclosed |