Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 20/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16774261 | 0.82 | ADORA3 (0.83) | ADORA3ADORA1ADORA2A | |
| SCHEMBL20122208 | 0.82 | ADORA3 (0.83) | ADORA3ADORA1ADORA2A | |
| SCHEMBL22359920 | 0.81 | ADORA3 (0.67) | ADORA3ADORA1ADORA2A | |
| SCHEMBL18352572 | 0.80 | ADORA3 (0.71) | ADORA3ADORA1ADORA2A | |
| SCHEMBL23097581 | 0.78 | ADORA3 (0.59) | ADORA3ADORA2A | |
| SCHEMBL20122153 | 0.77 | ADORA3 (0.66) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL23097580 | 0.77 | ADORA3 (0.69) | ADORA3ADORA2A | |
| SCHEMBL20122077 | 0.77 | ADORA3 (0.70) | ADORA3ADORA1ADORA2A | |
| SCHEMBL22359741 | 0.76 | ADORA3 (0.56) | ADORA3ADORA1ADORA2A | |
| SCHEMBL21939547 | 0.76 | ADORA3 (0.54) | ADORA3ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963450-B2 | A3 adenosine receptor agonists | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2018-05-08 | — | — | US | disclosed |