Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 16/20 | 0.66 |
| ▸ | TMIGD3 | P0DMS9 | 4/20 | 0.66 |
| ▸ | ADORA1 | P30542 | 14/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16774389 | 0.79 | ADORA3 (1.00) | ADORA3TMIGD3ADORA1ADORA2A | |
| SCHEMBL18352618 | 0.77 | ADORA3 (0.84) | ADORA3TMIGD3ADORA1ADORA2A | |
| SCHEMBL20122112 | 0.77 | ADORA3 (0.56) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL22757500 | 0.74 | ADORA3 (0.55) | ADORA3TMIGD3ADORA1ADORA2AADORA2B | |
| SCHEMBL22750488 | 0.74 | ADORA3 (0.57) | ADORA3TMIGD3ADORA1ADORA2AADORA2B | |
| SCHEMBL25566692 | 0.74 | ADORA3 (0.68) | ADORA3TMIGD3ADORA1ADORA2AADORA2B | |
| SCHEMBL12804929 | 0.72 | ADORA3 (1.00) | ADORA3TMIGD3ADORA1ADORA2A | |
| SCHEMBL22750588 | 0.70 | ADORA3 (0.56) | ADORA3TMIGD3ADORA1ADORA2AADORA2B | |
| SCHEMBL12805594 | 0.69 | ADORA3 (1.00) | ADORA3TMIGD3ADORA1ADORA2A | |
| SCHEMBL12805687 | 0.69 | ADORA3 (1.00) | ADORA3TMIGD3ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963450-B2 | A3 adenosine receptor agonists | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2018-05-08 | — | — | US | disclosed |