Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.59 |
| ▸ | HTR5A | P47898 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 16/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.52 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21758645 | 0.91 | ADORA3 (0.57) | HRH2HTR5AADORA3ADORA1ADORA2A | |
| SCHEMBL18352461 | 0.90 | ADORA3 (0.56) | HRH2HTR5AADORA3ADORA1ADORA2A | |
| SCHEMBL20122150 | 0.89 | ADORA3 (0.65) | ADORA3ADORA1ADORA2ATMIGD3 | |
| SCHEMBL21758637 | 0.89 | ADORA3 (0.65) | ADORA3ADORA1ADORA2ATMIGD3 | |
| SCHEMBL21758644 | 0.83 | ADORA3 (0.55) | HRH2HTR5AADORA3ADORA1ADORA2A | |
| SCHEMBL21758642 | 0.83 | ADORA3 (0.60) | ADORA3ADORA1ADORA2ATMIGD3 | |
| SCHEMBL21779288 | 0.82 | ADORA3 (0.45) | HRH2HTR5AADORA3ADORA1ADORA2A | |
| SCHEMBL16774095 | 0.82 | HRH2 (0.68) | HRH2HTR5AADORA3ADORA1ADORA2A | |
| SCHEMBL21779299 | 0.82 | HRH2 (0.68) | HRH2HTR5AADORA3ADORA1ADORA2A | |
| SCHEMBL18357883 | 0.82 | HRH2 (0.68) | HRH2HTR5AADORA3ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963450-B2 | A3 adenosine receptor agonists | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2018-05-08 | — | — | US | disclosed |