Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 20/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18358027 | 0.81 | ADORA3 (0.79) | ADORA3ADORA2AADORA1 | |
| SCHEMBL18352626 | 0.79 | ADORA3 (0.66) | ADORA3ADORA2AADORA1SLC6A2TMEM97 | |
| SCHEMBL24615152 | 0.78 | ADORA3 (0.70) | ADORA3ADORA2AADORA1 | |
| SCHEMBL24615162 | 0.74 | ADORA3 (0.69) | ADORA3ADORA1SLC6A2 | |
| SCHEMBL24615183 | 0.74 | SLC6A3 (0.66) | ADORA3SLC6A2 | |
| SCHEMBL24615151 | 0.73 | ADORA3 (0.71) | ADORA3ADORA2AADORA1 | |
| SCHEMBL20122181 | 0.72 | ADORA3 (0.47) | ADORA3ADORA2AADORA1 | |
| SCHEMBL10323827 | 0.68 | ADORA3 (1.00) | ADORA3ADORA2A | |
| SCHEMBL20122100 | 0.68 | ADORA3 (0.61) | ADORA3ADORA2AADORA1 | |
| SCHEMBL16361550 | 0.68 | ADORA3 (1.00) | ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963450-B2 | A3 adenosine receptor agonists | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2018-05-08 | — | — | US | disclosed |