Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.51 |
| ▸ | CTSK | P43235 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20094989 | 0.88 | MEN1 (0.45) | CTSSCTSKMEN1GAAKMT2A | |
| SCHEMBL12179560 | 0.86 | TDP1 (0.58) | CTSSCTSKMEN1GAAKMT2A | |
| SCHEMBL20094898 | 0.85 | CA1 (0.42) | CTSSCTSKMEN1GAAKMT2A | |
| SCHEMBL16504634 | 0.85 | MEN1 (0.58) | CTSSCTSKMEN1GAAKMT2A | |
| SCHEMBL16504731 | 0.85 | MEN1 (0.58) | CTSSCTSKMEN1GAAKMT2A | |
| SCHEMBL14378789 | 0.85 | MEN1 (0.58) | CTSSCTSKMEN1GAAKMT2A | |
| SCHEMBL16790483 | 0.85 | CTSS (0.44) | CTSSCTSKMEN1GAAKMT2A | |
| SCHEMBL12179561 | 0.84 | CTSS (0.55) | CTSSCTSKMEN1GAAKMT2A | |
| SCHEMBL12192760 | 0.83 | MEN1 (0.56) | CTSSCTSKMEN1GAAKMT2A | |
| SCHEMBL16909018 | 0.83 | SIRT5 (0.57) | CTSSCTSKMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963427-B2 | Dithiol mucolytic agents | PARION SCIENCES, INC. (US) | 2018-05-08 | — | — | US | disclosed |