Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20191171 | 1.00 | TDP1 (0.47) | TDP1MAOAMAOBADRA1APRMT1 | |
| SCHEMBL12155283 | 1.00 | TDP1 (0.47) | TDP1MAOAMAOBADRA1APRMT1 | |
| SCHEMBL18262806 | 0.99 | TDP1 (0.44) | TDP1MAOAMAOBADRA1APRMT1 | |
| SCHEMBL12514747 | 0.99 | TDP1 (0.44) | TDP1MAOAMAOBADRA1APRMT1 | |
| SCHEMBL1795152 | 0.99 | TDP1 (0.44) | TDP1MAOAMAOBADRA1APRMT1 | |
| SCHEMBL5490945 | 0.94 | MEN1 (0.43) | TDP1MAOAMAOBADRA1APRMT1 | |
| SCHEMBL2905985 | 0.94 | MEN1 (0.43) | TDP1MAOAMAOBADRA1APRMT1 | |
| SCHEMBL991815 | 0.92 | TDP1 (0.54) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL23796908 | 0.90 | MAOA (0.52) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL23796907 | 0.90 | MAOA (0.52) | TDP1MAOAMAOBMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3035923-B1 | DITHIOL MUCOLYTIC AGENTS | PARION SCIENCES INC (US) | 2019-09-25 | — | — | EP | disclosed |
| US-9963427-B2 | Dithiol mucolytic agents | PARION SCIENCES, INC. (US) | 2018-05-08 | — | — | US | disclosed |