Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18262806 | 1.00 | TDP1 (0.44) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL12514747 | 1.00 | TDP1 (0.44) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL20191171 | 0.99 | TDP1 (0.47) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL20122294 | 0.99 | TDP1 (0.47) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL12155283 | 0.99 | TDP1 (0.47) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL5490945 | 0.96 | MEN1 (0.43) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL2905985 | 0.96 | MEN1 (0.43) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL17234179 | 0.90 | MEN1 (0.39) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL16322976 | 0.90 | MEN1 (0.39) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL1793511 | 0.90 | MEN1 (0.39) | TDP1MAOAMAOBMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8975262-B2 | Synthetic mimetics of host defense and uses thereof | CELLCEUTIX CORPORATION (US) | 2015-03-10 | — | — | US | claimed |
| US-20130090345-A1 | Synthetic Mimetics Of Host Defense And Uses Thereof | POLYMEDIX, INC. (US) | 2013-04-11 | — | — | US | claimed |
| EP-2358380-A1 | SYNTHETIC MIMETICS OF HOST DEFENSE AND USES THEREOF | Polymedix, Inc. (US) | 2011-08-24 | — | — | EP | claimed |
| WO-2010062573-A1 | SYNTHETIC MIMETICS OF HOST DEFENSE AND USES THEREOF | POLYMEDIX, INC. (US) | 2010-06-03 | — | — | WO | claimed |
| US-20100105703-A1 | Synthetic Mimetics Of Host Defense And Uses Thereof | POLYMEDIX, INC. (US) | 2010-04-29 | — | — | US | claimed |
| WO-2016190227-A1 | NOVEL COMPOUND AND GRAVITY TROPISM REGULATOR | 国立大学法人東京農工大学 | 2016-12-01 | — | — | WO | disclosed |
| US-20150072997-A1 | ANTI-MALARIAL COMPOUNDS | POLYMEDIX, INC. | 2015-03-12 | — | — | US | disclosed |
| US-8975262-B2 | Synthetic mimetics of host defense and uses thereof | CELLCEUTIX CORPORATION (US) | 2015-03-10 | — | — | US | disclosed |
| US-8796275-B2 | Anti-malarial compounds | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2014-08-05 | — | — | US | disclosed |
| US-20130090345-A1 | Synthetic Mimetics Of Host Defense And Uses Thereof | POLYMEDIX, INC. (US) | 2013-04-11 | — | — | US | disclosed |
| US-8278309-B2 | Synthetic mimetics of host defense and uses thereof | POLYMEDIX, INC. (US) | 2012-10-02 | — | — | US | disclosed |
| EP-2358380-A1 | SYNTHETIC MIMETICS OF HOST DEFENSE AND USES THEREOF | Polymedix, Inc. (US) | 2011-08-24 | — | — | EP | disclosed |
| EP-2321275-A1 | ANTI-MALARIAL COMPOUNDS | Polymedix, Inc. (US) | 2011-05-18 | — | — | EP | disclosed |
| WO-2010062573-A1 | SYNTHETIC MIMETICS OF HOST DEFENSE AND USES THEREOF | POLYMEDIX, INC. (US) | 2010-06-03 | — | — | WO | disclosed |
| US-20100105703-A1 | Synthetic Mimetics Of Host Defense And Uses Thereof | POLYMEDIX, INC. (US) | 2010-04-29 | — | — | US | disclosed |
| US-20100081665-A1 | Anti-Malarial Compounds | CELLCEUTIX CORPORATION | 2010-04-01 | — | — | US | disclosed |
| WO-2010014573-A1 | ANTI-MALARIAL COMPOUNDS | POLYMEDIX, INC. (US) | 2010-02-04 | — | — | WO | disclosed |
| US-7163921-B1 | Peptide derivatives and medicinal compositions | NIPPON SHINYAKU CO., LTD. (JP) | 2007-01-16 | — | — | US | disclosed |
| EP-1275657-A1 | PEPTIDE DERIVATIVES AND MEDICINAL COMPOSITIONS | Nippon Shinyaku Co., Ltd. (JP) | 2003-01-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130090345-A1 | Synthetic Mimetics Of Host Defense And Uses Thereof | TLR3, MYD88, TLR5 | TDP1 4134/4885MAOA 1652/4885MAOB 2304/4885 |
| US-20100081665-A1 | Anti-Malarial Compounds | AADAC, ME2, HTRA2 | TDP1 3837/4885MAOA 1029/4885MAOB 1906/4885 |
| US-20100105703-A1 | Synthetic Mimetics Of Host Defense And Uses Thereof | TLR3, MYD88, TLR5 | TDP1 4134/4885MAOA 1652/4885MAOB 2304/4885 |
| US-20150072997-A1 | ANTI-MALARIAL COMPOUNDS | AADAC, ME2, HTRA2 | TDP1 3837/4885MAOA 1029/4885MAOB 1906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.