Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GLP1R | P43220 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20122296 | 0.95 | HDAC1 (0.49) | CAPN1HDAC1HDAC8CTSSCTSK | |
| SCHEMBL16505182 | 0.92 | CTSS (0.53) | CAPN1HDAC1CTSSCTSKCA1 | |
| SCHEMBL16505183 | 0.92 | CTSS (0.53) | CAPN1HDAC1CTSSCTSKCA1 | |
| SCHEMBL16504665 | 0.92 | CTSS (0.53) | CAPN1HDAC1CTSSCTSKCA1 | |
| SCHEMBL16505181 | 0.92 | CTSS (0.53) | CAPN1HDAC1CTSSCTSKCA1 | |
| SCHEMBL16504664 | 0.92 | CTSS (0.53) | CAPN1HDAC1CTSSCTSKCA1 | |
| SCHEMBL21664570 | 0.91 | TDP1 (0.49) | CAPN1HDAC1HDAC8CA1CA2 | |
| SCHEMBL12262209 | 0.91 | MEN1 (0.52) | CAPN1HDAC1CTSSCTSKCA1 | |
| SCHEMBL20122340 | 0.90 | CAPN1 (0.57) | CAPN1HDAC1HDAC8CTSSCTSK | |
| SCHEMBL19820011 | 0.90 | CAPN1 (0.55) | CAPN1HDAC1HDAC8CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963427-B2 | Dithiol mucolytic agents | PARION SCIENCES, INC. (US) | 2018-05-08 | — | — | US | disclosed |