Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20122337 | 0.95 | CAPN1 (0.54) | HDAC1HDAC8CAPN1TDP1MEN1 | |
| SCHEMBL21664570 | 0.95 | TDP1 (0.49) | HDAC1HDAC8CAPN1TDP1MEN1 | |
| SCHEMBL31467206 | 0.93 | TDP1 (0.51) | HDAC1HDAC8CAPN1TDP1MEN1 | |
| SCHEMBL5024804 | 0.91 | MEN1 (0.55) | TDP1MEN1KMT2APOLBNPSR1 | |
| SCHEMBL20902186 | 0.89 | CAPN1 (0.48) | HDAC1HDAC8CAPN1TDP1MEN1 | |
| SCHEMBL20122339 | 0.89 | MEN1 (0.55) | HDAC1HDAC8CAPN1TDP1MEN1 | |
| SCHEMBL3728197 | 0.88 | CAPN1 (0.46) | CAPN1TDP1MEN1KMT2APOLB | |
| SCHEMBL3728193 | 0.88 | CAPN1 (0.46) | CAPN1TDP1MEN1KMT2APOLB | |
| SCHEMBL14820488 | 0.87 | TDP1 (0.50) | CAPN1TDP1MEN1KMT2APOLB | |
| SCHEMBL30186579 | 0.87 | MEN1 (0.60) | CAPN1TDP1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963427-B2 | Dithiol mucolytic agents | PARION SCIENCES, INC. (US) | 2018-05-08 | — | — | US | disclosed |