Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20122566 | 0.90 | CHRM1 (0.34) | CHRM1TBXA2RADRA1AATML3MBTL1 | |
| SCHEMBL20122491 | 0.90 | ACE (0.36) | CHRM1TBXA2RADRA1ANFKB1NFKB2 | |
| SCHEMBL20122467 | 0.89 | TACR1 (0.36) | CHRM1TBXA2RADRA1AATMFOLH1 | |
| SCHEMBL20122464 | 0.88 | — | — | |
| SCHEMBL20122425 | 0.87 | FOLH1 (0.32) | CHRM1TBXA2RADRA1AFOLH1 | |
| SCHEMBL20122427 | 0.86 | CYP1A2 (0.33) | — | |
| SCHEMBL20122424 | 0.85 | CYP1A2 (0.30) | — | |
| SCHEMBL20122515 | 0.84 | ADRB2 (0.33) | CHRM1TBXA2RADRA1AFOLH1 | |
| SCHEMBL20122426 | 0.84 | — | — | |
| SCHEMBL20122548 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963428-B1 | Bucillamine prodrugs, pharmaceutical compositions thereof, and methods of use | Nguyen, Mark Quang (US) | 2018-05-08 | — | — | US | disclosed |