SCHEMBL20123151

SCHEMBL20123151

C=C(CC)c1cc(O)c(O)cc1C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
HPGD P15428 2/20 0.35
ALOX15 P16050 2/20 0.35
HSD17B10 Q99714 2/20 0.35
TSHR P16473 1/20 0.35
RECQL P46063 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
PKM P14618 2/20 0.34
KDM4E B2RXH2 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
MAPT P10636 1/20 0.34
G6PD P11413 1/20 0.34
CYP2C9 P11712 1/20 0.34
ALOX12 P18054 1/20 0.34
MAPK1 P28482 1/20 0.34
CYP2C19 P33261 1/20 0.34
CCR6 P51684 1/20 0.34
HIF1A Q16665 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19113576 0.77
SCHEMBL27470244 0.75 CYP3A4 (0.44) ALDH1A1ALOX15HSD17B10TSHRTDP1
SCHEMBL20156578 0.75 CYP3A4 (0.44) ALDH1A1ALOX15HSD17B10TSHRTDP1
SCHEMBL19558004 0.75 MAPT (0.39) ALDH1A1HPGDALOX15HSD17B10TSHR
SCHEMBL13284210 0.74 HSP90AB1 (0.52) ALDH1A1HPGDALOX15HSD17B10TSHR
SCHEMBL20133776 0.72 ESR1 (0.34) ESR1
SCHEMBL20156488 0.71 L3MBTL1 (0.36) ALDH1A1HPGDHSD17B10TSHRKDM4E
SCHEMBL12676202 0.70 CA12 (0.48) RECQLKDM4EMAPTGAACA12
SCHEMBL23742537 0.69 UHRF1 (0.36) CYP1A2
SCHEMBL14308410 0.69 HPGD (0.40) ALDH1A1HPGDALOX15HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3033405-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2018-05-09 EP disclosed