Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23370244 | 0.80 | L3MBTL1 (0.33) | L3MBTL1ALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL20156606 | 0.78 | FASN (0.37) | — | |
| SCHEMBL20156475 | 0.77 | VNN1 (0.40) | L3MBTL1ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL20156514 | 0.76 | FASN (0.35) | — | |
| SCHEMBL19113576 | 0.73 | — | — | |
| SCHEMBL21318015 | 0.72 | KDM4E (0.58) | L3MBTL1ALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL20156578 | 0.72 | CYP3A4 (0.44) | ALDH1A1MAPTHSD17B10TSHR | |
| SCHEMBL20123151 | 0.71 | ALDH1A1 (0.35) | ALDH1A1KDM4EGAAMAPTHSD17B10 | |
| SCHEMBL5945887 | 0.71 | TSHR (0.48) | L3MBTL1ALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL18192044 | 0.70 | TSHR (0.42) | L3MBTL1ALDH1A1KDM4EGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089904-A1 | HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS | 3-V BIOSCIENCES, INC. (US) | 2018-05-17 | — | — | WO | disclosed |