Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.81 |
| ▸ | RAB9A | P51151 | 7/20 | 0.81 |
| ▸ | GAA | P10253 | 5/20 | 0.81 |
| ▸ | NPC1 | O15118 | 4/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.81 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.81 |
| ▸ | THRB | P10828 | 2/20 | 0.81 |
| ▸ | RECQL | P46063 | 2/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.81 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.81 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL161436 | 0.93 | RAB9A (0.67) | MAPTRAB9AGAANPC1MAPK1 | |
| SCHEMBL23456042 | 0.92 | RAB9A (0.68) | MAPTRAB9AGAANPC1MAPK1 | |
| Hydrochloric Acid SCHEMBL163829 | 0.90 | GAA (0.64) | MAPTRAB9AGAANPC1MAPK1 | |
| SCHEMBL39057 | 0.90 | MAPT (1.00) | MAPTRAB9AGAANPC1MAPK1 | |
| SCHEMBL1459772 | 0.90 | MAPT (1.00) | MAPTRAB9AGAANPC1MAPK1 | |
| SCHEMBL13107871 | 0.86 | MAPT (0.58) | MAPTRAB9AGAANPC1MAPK1 | |
| SCHEMBL13127250 | 0.86 | MAPT (0.58) | MAPTRAB9AGAANPC1MAPK1 | |
| SCHEMBL7758813 | 0.83 | RAB9A (0.85) | MAPTRAB9AGAANPC1MAPK1 | |
| SCHEMBL12648780 | 0.83 | MAPT (0.85) | MAPTRAB9AGAANPC1MAPK1 | |
| SCHEMBL1921511 | 0.83 | MAPT (0.85) | MAPTRAB9AGAANPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588144-B1 | DETECTING TARGETS USING MASS TAGS AND MASS SPECTROMETRY | VENTANA MED SYST INC (US) | 2018-05-09 | — | — | EP | disclosed |