Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20014548 | 0.93 | HPGD (0.45) | HSD17B3HPGDL3MBTL1MAPTMMP12 | |
| SCHEMBL6962931 | 0.88 | HSD17B3 (0.50) | HSD17B3HPGDL3MBTL1MAPTMMP12 | |
| SCHEMBL20014881 | 0.88 | HSD17B3 (0.50) | HSD17B3HPGDL3MBTL1MAPTMMP12 | |
| SCHEMBL3772410 | 0.81 | HSD17B3 (0.43) | HSD17B3HPGDMAPTMEN1KMT2A | |
| SCHEMBL20123676 | 0.79 | HSD17B3 (0.46) | HSD17B3MAPTCA1CA2CA4 | |
| SCHEMBL20123635 | 0.79 | HSD17B3 (0.46) | HSD17B3L3MBTL1MAPTCA1CA2 | |
| SCHEMBL31196698 | 0.79 | HTR2A (0.45) | HPGDL3MBTL1CA1CA2CA4 | |
| SCHEMBL31196699 | 0.79 | HTR2A (0.45) | HPGDL3MBTL1CA1CA2CA4 | |
| SCHEMBL6905658 | 0.79 | HTR2A (0.45) | HPGDL3MBTL1CA1CA2CA4 | |
| SCHEMBL13864431 | 0.77 | MAPT (0.50) | HSD17B3HPGDL3MBTL1MAPTMMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2620436-B1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO (JP) | 2018-05-09 | — | — | EP | disclosed |