Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | HK1 | P19367 | 1/20 | 0.36 |
| ▸ | GALK1 | P51570 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27607360 | 0.69 | AKR1B1 (0.36) | IDO1AKR1B1LMNAGAATSHR | |
| SCHEMBL6571089 | 0.69 | ALDH1A1 (0.36) | IDO1LMNATSHRMAPTALDH1A1 | |
| SCHEMBL8087155 | 0.68 | AKR1B1 (0.42) | AKR1B1LMNAGAATSHRHTT | |
| SCHEMBL20595301 | 0.67 | IDO1 (0.40) | IDO1LMNAGAATSHRHTT | |
| SCHEMBL1042744 | 0.66 | MAPT (0.41) | IDO1LMNAGAATSHRMAPT | |
| SCHEMBL6573768 | 0.66 | MEN1 (0.41) | IDO1LMNAGAATSHRMAPT | |
| Trifluoroacetic Acid SCHEMBL6241485 | 0.65 | MAPT (0.35) | IDO1LMNAGAATSHRMAPT | |
| SCHEMBL29352286 | 0.65 | MAPT (0.40) | IDO1LMNAGAATSHRMAPT | |
| SCHEMBL1120300 | 0.65 | MAPT (0.40) | IDO1LMNAGAATSHRMAPT | |
| SCHEMBL9302961 | 0.64 | MAPT (0.40) | IDO1LMNAGAATSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073662-A1 | COMBINATION OF A BENZOXAZINONE AND A FURTHER AGENT FOR TREATING RESPIRATORY DISEASES | ASTRAZENECA AB (SE) | 2011-06-23 | — | — | WO | disclosed |