Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4253259 | 0.82 | ALOX15 (0.47) | HTR2CHTR2AALDH1A1MAPTALOX15 | |
| SCHEMBL4263893 | 0.82 | HTR2A (0.38) | HTR2CHTR2AALDH1A1MAPTALOX15 | |
| SCHEMBL18761542 | 0.72 | ALOX15 (0.47) | HTR2CHTR2AALDH1A1MAPTALOX15 | |
| SCHEMBL10447051 | 0.71 | SLC6A2 (0.39) | HTR2CHTR2AALDH1A1GAAHTR2B | |
| SCHEMBL10446442 | 0.70 | ALDH1A1 (0.43) | HTR2CHTR2AALDH1A1MAPTGAA | |
| SCHEMBL2258698 | 0.68 | HTR2C (0.53) | HTR2CHTR2AALDH1A1CHRNA7CA1 | |
| SCHEMBL19593081 | 0.68 | ALOX15 (0.43) | HTR2CHTR2AALDH1A1MAPTALOX15 | |
| SCHEMBL16385859 | 0.68 | NR3C2 (0.43) | HTR2CHTR2AALDH1A1GAAHTR2B | |
| SCHEMBL10446495 | 0.67 | HSD17B3 (0.45) | HTR2CHTR2AALDH1A1MAPTGAA | |
| SCHEMBL10447311 | 0.67 | HTR2C (0.39) | HTR2CHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2620436-B1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO (JP) | 2018-05-09 | — | — | EP | disclosed |