Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 4/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.33 |
| ▸ | FAP | Q12884 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2013234 | 0.71 | ALDH1A1 (0.47) | P2RX7ALDH1A1MEN1KMT2A | |
| SCHEMBL17101190 | 0.62 | KMT2A (0.46) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL363390 | 0.61 | PPARG (0.43) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL10483592 | 0.61 | DPP4 (0.48) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL2013353 | 0.60 | CACNA1G (0.45) | ALDH1A1MEN1KMT2A | |
| SCHEMBL27559397 | 0.60 | KMT2A (0.51) | DPP4DPP7ALDH1A1KMT2A | |
| SCHEMBL29187310 | 0.60 | PPARG (0.46) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL26076505 | 0.60 | PPARG (0.46) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL7437418 | 0.59 | KMT2A (0.58) | ALDH1A1KMT2A | |
| SCHEMBL5607417 | 0.58 | DPP4 (0.42) | DPP4DPP8DPP9FAPDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513069-A1 | ANTIFUNGAL COMPOUNDS | Katholieke Universiteit Leuven (BE) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011072345-A1 | ANTIFUNGAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2011-06-23 | — | — | WO | disclosed |