Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 13/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12067575 | 0.70 | PDE10A (0.52) | PDE10A | |
| SCHEMBL15033445 | 0.69 | PDE10A (0.65) | PDE10A | |
| SCHEMBL18911313 | 0.65 | PDE10A (0.49) | PDE10A | |
| SCHEMBL10271750 | 0.62 | JAK2 (0.46) | PDE10A | |
| SCHEMBL7147342 | 0.62 | PDE10A (0.46) | PDE10A | |
| SCHEMBL11413826 | 0.60 | PDE10A (0.44) | PDE10A | |
| SCHEMBL14006974 | 0.60 | LMNA (0.49) | PDE10A | |
| SCHEMBL15959361 | 0.60 | PARP1 (0.36) | — | |
| SCHEMBL14352211 | 0.60 | PDE10A (0.46) | PDE10A | |
| SCHEMBL2717765 | 0.59 | JAK2 (0.46) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318561-B1 | HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC (US) | 2021-12-22 | — | — | EP | disclosed |
| EP-2576540-B1 | HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC (US) | 2019-09-04 | — | — | EP | disclosed |
| EP-3318561-A1 | HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | Sunovion Pharmaceuticals Inc. (US) | 2018-05-09 | — | — | EP | disclosed |