Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | PRF1 | P14222 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20124031 | 0.80 | MAOA (0.42) | TDP2MAOAPRF1 | |
| SCHEMBL20923984 | 0.68 | MAOA (0.57) | TDP2MAOA | |
| SCHEMBL29845878 | 0.68 | MAOA (0.57) | TDP2MAOA | |
| SCHEMBL29411064 | 0.66 | CYP3A4 (0.50) | MAOA | |
| SCHEMBL273350 | 0.66 | CYP3A4 (0.50) | MAOA | |
| SCHEMBL21695847 | 0.65 | MAPT (0.54) | TDP2 | |
| Hydrochloric Acid SCHEMBL25305777 | 0.64 | CYP3A4 (0.48) | MAOA | |
| SCHEMBL20924224 | 0.62 | KDM1A (0.50) | MAOA | |
| SCHEMBL18956824 | 0.59 | HDAC4 (0.47) | — | |
| SCHEMBL16334825 | 0.59 | HDAC4 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2686298-B1 | SUBSTITUTED DIPHENYL DERIVATIVES | CREATIVE THERAPEUTICS GMBH (DE) | 2018-05-09 | — | — | EP | disclosed |