Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MECP2 | P51608 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20124017 | 0.80 | TDP2 (0.32) | MAOATDP2PRF1 | |
| SCHEMBL25985744 | 0.70 | MAOA (0.54) | MAOAMAP4K4MAPTALDH1A1KDM4E | |
| SCHEMBL29471388 | 0.68 | MAOA (0.68) | MAOAMAP4K4MAPTALDH1A1KDM4E | |
| SCHEMBL2023695 | 0.68 | MAOA (0.68) | MAOAMAP4K4MAPTALDH1A1KDM4E | |
| SCHEMBL29700245 | 0.68 | CHRNB4 (0.36) | HTR6CYP3A4 | |
| SCHEMBL9329744 | 0.68 | HSD17B1 (0.44) | KDM4EMEN1KMT2ATDP2CYP3A4 | |
| SCHEMBL30643801 | 0.68 | TP53 (0.37) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL170839 | 0.67 | ALDH1A1 (0.39) | HTR6MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL29598333 | 0.67 | ALDH1A1 (0.39) | HTR6MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL2442271 | 0.66 | MAOA (0.65) | MAOAMAP4K4MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2686298-B1 | SUBSTITUTED DIPHENYL DERIVATIVES | CREATIVE THERAPEUTICS GMBH (DE) | 2018-05-09 | — | — | EP | disclosed |