Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 20/20 | 0.41 |
| ▸ | CA1 | P00915 | 19/20 | 0.41 |
| ▸ | CA9 | Q16790 | 16/20 | 0.37 |
| ▸ | CA12 | O43570 | 5/20 | 0.34 |
| ▸ | CA7 | P43166 | 5/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.34 |
| ▸ | CA3 | P07451 | 4/20 | 0.34 |
| ▸ | CA4 | P22748 | 4/20 | 0.34 |
| ▸ | CA6 | P23280 | 4/20 | 0.34 |
| ▸ | CA5A | P35218 | 4/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19348601 | 0.84 | — | — | |
| SCHEMBL1044669 | 0.76 | CA2 (0.45) | CA2CA1CA9CA12CA7 | |
| SCHEMBL11146088 | 0.72 | — | — | |
| SCHEMBL16938653 | 0.70 | ALDH1A1 (0.32) | — | |
| SCHEMBL9295282 | 0.69 | — | — | |
| SCHEMBL28162307 | 0.69 | — | — | |
| SCHEMBL11146048 | 0.68 | ALDH1A1 (0.32) | — | |
| SCHEMBL11146045 | 0.68 | ALDH1A1 (0.32) | — | |
| SCHEMBL18196229 | 0.66 | — | — | |
| SCHEMBL2222102 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2686298-B1 | SUBSTITUTED DIPHENYL DERIVATIVES | CREATIVE THERAPEUTICS GMBH (DE) | 2018-05-09 | — | — | EP | disclosed |