Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.50 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.50 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.50 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8230248 | 0.86 | EPHX1 (0.53) | EPHX1GNAI3GNAO1GNAI1POLB | |
| SCHEMBL23080304 | 0.84 | SMN1; SMN2 (0.47) | EPHX1HSD11B1EPHX2SMN1; SMN2HPGD | |
| SCHEMBL12336001 | 0.81 | GNAI3 (0.53) | EPHX1GNAI3GNAO1GNAI1POLB | |
| SCHEMBL12308796 | 0.78 | GNAI3 (0.46) | EPHX1GNAI3GNAO1GNAI1POLB | |
| SCHEMBL18531851 | 0.78 | GNAI3 (0.60) | EPHX1GNAI3GNAO1GNAI1POLB | |
| SCHEMBL617591 | 0.76 | GNAI3 (0.62) | EPHX1GNAI3GNAO1GNAI1POLB | |
| Hydrochloric Acid SCHEMBL6163168 | 0.74 | GNAI3 (0.65) | EPHX1GNAI3GNAO1GNAI1POLB | |
| SCHEMBL27224567 | 0.74 | EPHX1 (0.57) | EPHX1GNAI3GNAO1GNAI1POLB | |
| SCHEMBL5106542 | 0.74 | EPHX1 (0.61) | EPHX1GNAI3GNAO1GNAI1POLB | |
| Pivalate SCHEMBL28282777 | 0.73 | GNAI3 (0.48) | EPHX1GNAI3GNAO1GNAI1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488532-B1 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | MELINTA THERAPEUTICS INC (US) | 2018-05-09 | — | — | EP | disclosed |