Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 3/20 | 0.62 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.62 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.62 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6163168 | 0.98 | GNAI3 (0.65) | GNAI3GNAO1GNAI1EPHX1POLB | |
| Acetic Acid SCHEMBL9471908 | 0.94 | GNAI3 (0.57) | GNAI3GNAO1GNAI1EPHX1POLB | |
| SCHEMBL10444151 | 0.88 | KCNH2 (0.52) | GNAI3GNAO1GNAI1EPHX1POLB | |
| SCHEMBL4782330 | 0.88 | KCNH2 (0.52) | GNAI3GNAO1GNAI1EPHX1POLB | |
| SCHEMBL12403611 | 0.88 | KCNH2 (0.52) | GNAI3GNAO1GNAI1EPHX1POLB | |
| Hydrochloric Acid SCHEMBL17560472 | 0.86 | GNAI3 (0.53) | GNAI3GNAO1GNAI1EPHX1POLB | |
| Hydrochloric Acid SCHEMBL28301968 | 0.86 | GNAI3 (0.53) | GNAI3GNAO1GNAI1EPHX1POLB | |
| Hydrochloric Acid SCHEMBL2013464 | 0.86 | GNAI3 (0.53) | GNAI3GNAO1GNAI1EPHX1POLB | |
| Hydrochloric Acid SCHEMBL28060427 | 0.86 | GNAI3 (0.53) | GNAI3GNAO1GNAI1EPHX1POLB | |
| SCHEMBL256673 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250115571-A1 | OXOPIPERAZINE DERIVATIVES | Inthera Bioscience AG (CH) | 2025-04-10 | — | — | US | disclosed |
| US-20250073217-A1 | SMALL MOLECULE ADRENORECEPTOR ANTAGONISTS AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2025-03-06 | — | — | US | disclosed |
| US-12012393-B2 | Oxopiperazine derivatives | Inthera Bioscience AG (CH) | 2024-06-18 | — | — | US | disclosed |
| EP-3724178-B1 | 1-(PIPERIDINOCARBONYLMETHYL)-2-OXOPIPERAZINE DERIVATIVES FOR TREATING CANCER | Inthera Bioscience AG (CH) | 2024-05-01 | — | — | EP | disclosed |
| EP-3873600-B9 | PYRIDINYL SULFONAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2024-02-14 | — | — | EP | disclosed |
| EP-3873600-B1 | PYRIDINYL SULFONAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2023-09-20 | — | — | EP | disclosed |
| WO-2023133135-A2 | SMALL MOLECULE ADRENORECEPTOR ANTAGONISTS AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2023-07-13 | — | — | WO | disclosed |
| EP-3183232-B1 | SUBSTITUTED 1-ARYLETHYL-4-ACYLAMINOPIPERIDINE DERIVATIVES AS OPIOID/ALPHA-ADRENORECEPTOR MODULATORS AND METHOD OF THEIR PREPARATION | UNIV ARIZONA (US) | 2023-05-03 | — | — | EP | disclosed |
| EP-3183232-B1 | SUBSTITUTED 1-ARYLETHYL-4-ACYLAMINOPIPERIDINE DERIVATIVES AS OPIOID/ALPHA-ADRENORECEPTOR MODULATORS AND METHOD OF THEIR PREPARATION | UNIV ARIZONA (US) | 2023-05-03 | — | — | EP | disclosed |
| CN-115785074-A | PARP7 inhibitors and uses thereof | 诺沃斯达药业(上海)有限公司 | 2023-03-14 | — | — | CN | disclosed |
| WO-2009121063-A2 | CHEMOKINE RECEPTOR MODULATORS | ALTIRIS THERAPEUTICS (US) | 2009-10-01 | — | — | WO | disclosed |
| WO-2009106534-A1 | NOVEL HETEROCYCLIC CARBOXAMIDES AS M1 AGONISTS | H. LUNDBECK A/S (DK) | 2009-09-03 | — | — | WO | disclosed |
| US-20090156465-A1 | DERIVATIVES OF BETA-AMINO ACID AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2009-06-18 | — | — | US | disclosed |
| US-20080255083-A1 | NEW PYRIDONE DERIVATES WITH MCH ANTAGONISTIC ACTIVITY AND MEDICAMENTS COMPRISING THESE COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-16 | — | — | US | disclosed |
| US-20080176883-A1 | Antiinflammtory, antiproliferative, anticancer agents; (3-Hydroxy-pyrrolidin-1-yl)-(3-trifluoromethyl-7,8-dihydro-5H-[1,6]naphthyridin-6-yl)-methanone | ABBVIE INC. | 2008-07-24 | — | — | US | disclosed |
| US-20070049603-A1 | Raf inhibitor compounds and methods of use thereof | ARRAY BIOPHARMA INC. | 2007-03-01 | — | — | US | disclosed |
| CN-1071329-C | Aryl glycinamide derivatives, methods of producing these substances and pharmaceutical compositions containing such compounds | BOEHRINGER INGELHEIM KG (DE) | 2001-09-19 | — | — | CN | disclosed |
| CN-1180352-A | Aryl glycinamide derivatives, methods of producing these substances and pharmaceutical compositions containing such compounds | BOEHRINGER INGELHEIM KG (DE) | 1998-04-29 | — | — | CN | disclosed |
| EP-0457686-A1 | Novel aminopiperidine, aminopyrrolidine and aminoperhydroazepine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1991-11-21 | — | — | EP | disclosed |
| CN-87100040-A | The alkylamine that alkyl diaryl replaces, its preparation technology's method, the medicine of using and containing this compounds | — | 1987-09-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176883-A1 | Antiinflammtory, antiproliferative, anticancer agents; (3-Hydroxy-pyrrolidin-1-yl)-(3-trifluoromethyl-7,8-dihydro-5H-[1,6]naphthyridin-6-yl)-methanone | MIF, CCL5, CCR2 | GNAI3 1252/4885GNAO1 1367/4885GNAI1 786/4885 |
| US-20070049603-A1 | Raf inhibitor compounds and methods of use thereof | BRAF, RAF1, ARAF | GNAI3 437/4885GNAO1 1098/4885GNAI1 275/4885 |
| US-20250115571-A1 | OXOPIPERAZINE DERIVATIVES | CYP3A5, AQP1, AVPR2 | GNAI3 466/4885GNAO1 927/4885GNAI1 410/4885 |
| US-20080255083-A1 | NEW PYRIDONE DERIVATES WITH MCH ANTAGONISTIC ACTIVITY AND MEDICAMENTS COMPRISING THESE COMPOUNDS | MCHR1, MCHR2, GPR119 | GNAI3 3736/4885GNAO1 2821/4885GNAI1 3600/4885 |
| US-20250073217-A1 | SMALL MOLECULE ADRENORECEPTOR ANTAGONISTS AND USES THEREOF | OPRL1, OPRK1, OPRM1 | GNAI3 164/4885GNAO1 179/4885GNAI1 178/4885 |
| US-12012393-B2 | Oxopiperazine derivatives | CYP3A5, AQP1, AVPR2 | GNAI3 466/4885GNAO1 927/4885GNAI1 410/4885 |
| US-20090156465-A1 | DERIVATIVES OF BETA-AMINO ACID AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS | DPP4, DPP3, DPP7 | GNAI3 3716/4885GNAO1 4547/4885GNAI1 4026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.