Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 3/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28789802 | 0.80 | EPHX1 (0.39) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL11774316 | 0.74 | ADH1C (0.37) | EPHX1TP53SHBG | |
| SCHEMBL18656210 | 0.72 | — | — | |
| SCHEMBL11771185 | 0.71 | EPHX1 (0.39) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL11024126 | 0.70 | EPHX1 (0.39) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL1170371 | 0.66 | TP53 (0.52) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL22606844 | 0.66 | EPHX1 (0.43) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL22191947 | 0.66 | EPHX1 (0.43) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL10012157 | 0.66 | TP53 (0.52) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL6853792 | 0.66 | EPHX1 (0.43) | EPHX1TP53KDM4EGMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2543991-B1 | URACIL-SPECIFIC FLUORESCENCE DETECTION REACTION AND METHOD FOR EXAMINING DIHYDROPYRIMIDINE DEHYDROGENASE DEFICIENCY | UNIV NAGASAKI (JP) | 2018-05-09 | — | — | EP | disclosed |