Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11077257 | 0.73 | — | — | |
| SCHEMBL13658772 | 0.73 | — | — | |
| SCHEMBL9419674 | 0.69 | ALDH1A1 (0.41) | KDM4E | |
| SCHEMBL1961336 | 0.67 | ADH1B (0.52) | KDM4E | |
| SCHEMBL24693886 | 0.65 | EPHX1 (0.40) | KDM4E | |
| SCHEMBL30891548 | 0.64 | ALDH1A1 (0.44) | KDM4E | |
| SCHEMBL10045264 | 0.63 | CYP2C19 (0.46) | KDM4E | |
| SCHEMBL22824355 | 0.63 | ADH1B (0.47) | — | |
| SCHEMBL840536 | 0.62 | ALDH1A1 (0.43) | KDM4E | |
| SCHEMBL842217 | 0.62 | ALDH1A1 (0.43) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3130343-B1 | POLYIMIDAZOLES FOR USE AS BILE ACID SEQUESTRANTS | RELYPSA INC (US) | 2018-05-09 | — | — | EP | disclosed |