Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 2/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19731973 | 0.83 | LIMK1 (0.34) | LIMK1CLK1KDM4EMAPTMEN1 | |
| SCHEMBL20858439 | 0.68 | KDM4E (0.36) | LIMK1CLK1KDM4EMAPTMEN1 | |
| SCHEMBL10054253 | 0.68 | LIMK1 (0.57) | LIMK1CLK1KDM4EMAPTALDH1A1 | |
| SCHEMBL20041730 | 0.66 | NPC1 (0.37) | LIMK1CLK1KDM4EMAPTMEN1 | |
| SCHEMBL25467714 | 0.64 | LIMK1 (0.36) | LIMK1CLK1KDM4EPOLBALDH1A1 | |
| SCHEMBL17127170 | 0.64 | PIM1 (0.40) | LIMK1CLK1KDM4EMAPTMEN1 | |
| SCHEMBL720703 | 0.63 | HSP90AA1 (0.41) | LIMK1CLK1KDM4EMAPTMEN1 | |
| SCHEMBL24623724 | 0.61 | LIMK1 (0.46) | LIMK1CLK1KDM4EMAPTALDH1A1 | |
| SCHEMBL17051494 | 0.60 | LIMK1 (0.49) | LIMK1CLK1KDM4EMAPTPOLB | |
| SCHEMBL149872 | 0.60 | GPR3 (0.54) | LIMK1CLK1KDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318566-A1 | AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS | UDC Ireland Limited (IE) | 2018-05-09 | — | — | EP | disclosed |