Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL720703 | 0.78 | HSP90AA1 (0.41) | NPC1HSP90AA1L3MBTL1LIMK1CLK1 | |
| SCHEMBL18427351 | 0.74 | TUBB4A (0.50) | NPC1L3MBTL1KDM4EALDH1A1MEN1 | |
| SCHEMBL22915065 | 0.71 | KDM4E (0.32) | NPC1HSP90AA1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL13763321 | 0.71 | HSP90AA1 (0.48) | NPC1HSP90AA1L3MBTL1LIMK1CLK1 | |
| SCHEMBL24201041 | 0.70 | L3MBTL1 (0.49) | NPC1HSP90AA1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL18386661 | 0.70 | ALDH1A1 (0.40) | NPC1L3MBTL1KDM4EALDH1A1MEN1 | |
| SCHEMBL10033652 | 0.69 | HSP90AA1 (0.42) | NPC1HSP90AA1L3MBTL1LIMK1CLK1 | |
| SCHEMBL21841136 | 0.69 | L3MBTL1 (0.56) | NPC1HSP90AA1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL19699885 | 0.68 | LIMK1 (0.49) | NPC1HSP90AA1L3MBTL1LIMK1CLK1 | |
| SCHEMBL14368872 | 0.68 | KDM4E (0.46) | NPC1HSP90AA1L3MBTL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2982676-B1 | Benzimidazo[2,1-B]benzoxazoles for electronic applications | IDEMITSU KOSAN CO (JP) | 2018-04-11 | — | — | EP | disclosed |