Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20124331 | 0.81 | ADORA1 (0.46) | ADORA1EGFRMAPTADORA2BKDM4E | |
| SCHEMBL23652501 | 0.80 | ADORA1 (0.35) | ADORA1EGFRMAPTADORA2BKDM4E | |
| SCHEMBL21913548 | 0.75 | MAPT (0.40) | MAPTKDM4EALDH1A1L3MBTL1NPC1 | |
| SCHEMBL20094136 | 0.74 | ADORA1 (0.37) | ADORA1EGFRMAPTADORA2BKDM4E | |
| SCHEMBL21698371 | 0.71 | HSD11B1 (0.40) | ADORA1ADORA2BALDH1A1NPC1RAB9A | |
| SCHEMBL25638911 | 0.70 | KDM4E (0.43) | MAPTKDM4EALDH1A1L3MBTL1NPC1 | |
| SCHEMBL21415870 | 0.68 | KDM4E (0.41) | MAPTKDM4EALDH1A1L3MBTL1NPC1 | |
| SCHEMBL19054923 | 0.68 | KDM4E (0.41) | MAPTKDM4EALDH1A1L3MBTL1NPC1 | |
| SCHEMBL20124327 | 0.67 | ADORA1 (0.47) | ADORA1EGFRMAPTADORA2BKDM4E | |
| SCHEMBL20124326 | 0.67 | KDM4E (0.43) | MAPTKDM4EALDH1A1L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318566-A1 | AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS | UDC Ireland Limited (IE) | 2018-05-09 | — | — | EP | disclosed |